Universal sample requirements for molecular diagnostics
Strategies to deal with common challenges
Challenges unique to PCR assays
Challenges unique to DNA fluorescent assays
Challenges unique to NGS assays
Challenges unique to newer molecular technologies
Since the beginning of the PCR revolution in the 1980s, molecular diagnostics have proven to be a useful tool for the clinical laboratory. The ability to analyze a variety of samples for DNA and RNA content have proven to be useful for a large number of clinical conditions using a number of different technologies. However, each technology has its pitfalls with how to handle samples for optimal results. In addition, different technologies have different challenges as to what can inhibit optimal results, and each technology has a unique solution to these pitfalls.
Todd Graham , is a masters-level bench scientist and medical technologist with a host of experience in both the clinical diagnostics and biotechnology fields. He has work for a number of start-up firms in the clinical diagnostics and biotechnology industries, as well as worked for larger firms within both industries. He has a broad level of expertise in assay development for quality control, pharmaceutical development and clinical diagnostics.
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